发明公开
EP2681330A1 USE OF THE OLFACTOMEDIN-4 PROTEIN (OLFM4) IN COLORECTAL CANCER DIAGNOSIS
有权
VERWENDUNG DES OLFACTOMEDIN-4-PROTEIN（OLFM4）BEI DER DIAGNOSE VON KOLOREKTALKARZINOM
- 专利标题： USE OF THE OLFACTOMEDIN-4 PROTEIN (OLFM4) IN COLORECTAL CANCER DIAGNOSIS
- 专利标题（中）： VERWENDUNG DES OLFACTOMEDIN-4-PROTEIN（OLFM4）BEI DER DIAGNOSE VON KOLOREKTALKARZINOM
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申请号： EP11719644.4申请日： 2011-03-02
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公开(公告)号： EP2681330A1公开(公告)日： 2014-01-08
- 发明人: GUETTE, Catherine , COQUERET, Olivier , BARRE, Benjamin , GAMELIN, Erick
- 申请人： Institut de Cancérologie de l'Ouest (I.C.O)
- 申请人地址： 2 Rue Moll 49100 Angers FR
- 专利权人： Institut de Cancérologie de l'Ouest (I.C.O)
- 当前专利权人： Institut de Cancérologie de l'Ouest (I.C.O)
- 当前专利权人地址： 2 Rue Moll 49100 Angers FR
- 代理机构： Regimbeau
- 国际公布： WO2012117267 20120907
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting the responds to a chemotherapeutic agent of a subject suffering from a colorectal cancer: according to the present invention, the by determining the OLFM4 levels. According to the present invention, the response can be predicted by determining the OLFM4 levels. This result in turn permits the design or the adaptation of a treatment of the said subject with the said chemotherapeutic agent.
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