发明公开
EP2683399A2 METHODS FOR DIAGNOSING AND/OR TREATING STERILITY
审中-公开
VERFAHREN ZUR DIAGNOSE UND / ODER BEHANDLUNG VONSTERILITÄT
- 专利标题： METHODS FOR DIAGNOSING AND/OR TREATING STERILITY
- 专利标题（中）： VERFAHREN ZUR DIAGNOSE UND / ODER BEHANDLUNG VONSTERILITÄT
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申请号： EP12707757.6申请日： 2012-03-07
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公开(公告)号： EP2683399A2公开(公告)日： 2014-01-15
- 发明人: CONTI, Marc , LORIC, Sylvain , MANIVET, Philippe , CARADEC, Josselin , KEUMEUGNI KWEMO, Carlosse , MATAR, Corine , REVAUD, Déborah
- 申请人： Bioquanta , Bioquanta Corp. , Assistance Publique Hôpitaux De Paris
- 申请人地址： 5 rue l'abbé de l'Epée 75005 Paris FR
- 专利权人： Bioquanta,Bioquanta Corp.,Assistance Publique Hôpitaux De Paris
- 当前专利权人： Bioquanta,Bioquanta Corp.,Assistance Publique Hôpitaux De Paris
- 当前专利权人地址： 5 rue l'abbé de l'Epée 75005 Paris FR
- 代理机构： Sutto, Luca
- 优先权： EP11305236 20110307; US201161450409P 20110308
- 国际公布： WO2012120038 20120913
- 主分类号： A61K38/57
- IPC分类号： A61K38/57 ; A61P15/08 ; G01N33/50
摘要：
The present invention concerns a polypeptide comprising the N-terminal fragment of a cystatin, and/or a cystatin expression inducer for use for the treatment of sterility and/or infertility, and a method of diagnosing and/or predicting sterility and/or infertility of a subject and/or of a couple of subjects, which method comprises measuring the level of at least one cystatin in a biological sample of a male subject and/or measuring the level of at least one cystatin in a biological sample of a female subject, and optionally measuring further the level of at least one cathepsin in a biological sample of said male of female subject.
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