发明公开
EP2699253A4 STREPTOCOCCUS BACTERIOPHAGE LYSINS FOR DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIA
有权
EN US US EN EN EN Z Z EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN
- 专利标题: STREPTOCOCCUS BACTERIOPHAGE LYSINS FOR DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIA
- 专利标题(中): EN US US EN EN EN Z Z EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN
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申请号: EP12773653申请日: 2012-04-20
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公开(公告)号: EP2699253A4公开(公告)日: 2015-07-01
- 发明人: FISCHETTI VINCENT A , SCHMITZ JONATHAN , GILMER DANIEL , EULER CHAD
- 申请人: UNIV ROCKEFELLER
- 专利权人: UNIV ROCKEFELLER
- 当前专利权人: UNIV ROCKEFELLER
- 优先权: US201161477836 2011-04-21
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61P31/04
摘要:
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus , and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.
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