发明公开
EP2699553A1 SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
审中-公开
取代DIAMINOCARBOXAMID-和DIAMINOCARBONITRILPYRIMIDINE，THEREOF组合物和治疗方法，这些方法
- 专利标题： SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
- 专利标题（中）： 取代DIAMINOCARBOXAMID-和DIAMINOCARBONITRILPYRIMIDINE，THEREOF组合物和治疗方法，这些方法
-
申请号： EP12718524.7申请日： 2012-04-20
-
公开(公告)号： EP2699553A1公开(公告)日： 2014-02-26
- 发明人: BENNETT, Brydon, L. , ELSNER, Jan , ERDMAN, Paul , HILGRAF, Robert , LEBRUN, Laurie, Ann , MCCARRICK, Meg , MOGHADDAM, Mehran, F. , NAGY, Mark, A. , NORRIS, Stephen , PAISNER, David, A. , SLOSS, Marianne , ROMANOW, William, J. , SATOH, Yoshitaka , TIKHE, Jayashree , YOON, Won, Hyung , DELGADO, Mercedes
- 申请人： Signal Pharmaceuticals, LLC
- 申请人地址： 4550 Towne Centre Court San Diego, CA 92121 US
- 专利权人： Signal Pharmaceuticals, LLC
- 当前专利权人： Signal Pharmaceuticals, LLC
- 当前专利权人地址： 4550 Towne Centre Court San Diego, CA 92121 US
- 代理机构： Jones Day
- 优先权： US201161478076P 20110422; US201161555339P 20111103
- 国际公布： WO2012145569 20121026
- 主分类号： C07D239/48
- IPC分类号： C07D239/48 ; C07D405/02 ; C07D401/12 ; C07D409/12
摘要：
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R
1 , R
2 , R
3, and R
4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
1 , R
2 , R
3, and R
4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
公开/授权文献
信息查询
