发明公开
EP2702148A1 YARROWIA PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PROMOTER REGIONS FOR GENE EXPRESSION IN YEAST
审中-公开
过氧化物酶体2.4二烯酰COA REDUKTASEPROMOTERREGIONEN OFF耶氏在酵母基因表达
- 专利标题： YARROWIA PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PROMOTER REGIONS FOR GENE EXPRESSION IN YEAST
- 专利标题（中）： 过氧化物酶体2.4二烯酰COA REDUKTASEPROMOTERREGIONEN OFF耶氏在酵母基因表达
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申请号： EP12712873.4申请日： 2012-04-02
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公开(公告)号： EP2702148A1公开(公告)日： 2014-03-05
- 发明人: ZHU, Quinn Qun , HONG, Seung-Pyo
- 申请人： E.I. Du Pont De Nemours and Company
- 申请人地址： 1007 Market Street Wilmington, Delaware 19898 US
- 专利权人： E.I. Du Pont De Nemours and Company
- 当前专利权人： E.I. Du Pont De Nemours and Company
- 当前专利权人地址： 1007 Market Street Wilmington, Delaware 19898 US
- 代理机构： Matthews, Derek Peter
- 优先权： US201161472742P 20110407
- 国际公布： WO2012138612 20121011
- 主分类号： C12N9/00
- IPC分类号： C12N9/00 ; C12P7/64
摘要：
Promoter regions associated with the
Yarrowia lipolytica peroxisomal 2,4-dienoyl-CoA reductase (
SPS19 ) gene are disclosed and have been found to be particularly effective for the expression of heterologous genes in yeast. These promoter regions will be useful for driving high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids.
Yarrowia lipolytica peroxisomal 2,4-dienoyl-CoA reductase (
SPS19 ) gene are disclosed and have been found to be particularly effective for the expression of heterologous genes in yeast. These promoter regions will be useful for driving high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids.
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