发明公开
EP2707524A2 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
审中-公开
肾损伤和肾功能衰竭的诊断和预后的方法和组合物
- 专利标题： METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
- 专利标题（中）： 肾损伤和肾功能衰竭的诊断和预后的方法和组合物
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申请号： EP12781602.3申请日： 2012-05-12
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公开(公告)号： EP2707524A2公开(公告)日： 2014-03-19
- 发明人: ANDERBERG, Joseph , GRAY, Jeff , McPHERSON, Paul , NAKAMURA, Kevin , KAMPF, James, Patrick
- 申请人： Astute Medical, Inc.
- 申请人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 专利权人： Astute Medical, Inc.
- 当前专利权人： Astute Medical, Inc.
- 当前专利权人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 代理机构： Schiweck, Weinzierl & Koch
- 优先权： US201161485576P 20110512; US201161485577P 20110512; US201161485579P 20110512; US201161485588P 20110512
- 国际公布： WO2012155123 20121115
- 主分类号： C40B30/04
- IPC分类号： C40B30/04 ; G01N33/53
摘要：
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Transforming growth factor beta-1, Transforming growth factor beta-2, Transforming growth factor beta-3, and Interleukin-1 receptor-like 1 as diagnostic and prognostic biomarkers in renal injuries.
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