- 专利标题： Baclofen and acamprosate based therapy of neurological disorders
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申请号： EP13196461.1申请日： 2012-03-01
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公开(公告)号： EP2727588B1公开(公告)日： 2018-08-29
- 发明人: Cohen, Daniel , Chumakov, Ilya , Nabirochkin, Serguei , Vial, Emmanuel , Guedj, Mickaël
- 申请人： Pharnext
- 申请人地址： 11, rue des Peupliers 92130 Issy-les-Moulineaux FR
- 专利权人： Pharnext
- 当前专利权人： Pharnext
- 当前专利权人地址： 11, rue des Peupliers 92130 Issy-les-Moulineaux FR
- 代理机构： Becker, Philippe
- 优先权： EP11305217 20110301; US201161468658P 20110329; EP11305687 20110606; US201161493606P 20110606
- 主分类号： A61K31/137
- IPC分类号： A61K31/137 ; A61K31/138 ; A61K31/185 ; A61K31/195 ; A61K31/42 ; A61K31/64 ; A61P25/28 ; A61K45/06 ; A61K31/197 ; A61K31/445 ; A61K31/145 ; A61K31/164 ; A61K31/44 ; A61K31/428 ; A61K9/20
摘要：
The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ² toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
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