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1.发明公开Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level 审中-公开组合物，方法和使用了用于治疗糖尿病和相关疾病通过调节血糖值
公开(公告)号：EP2727587A1
公开(公告)日：2014-05-07
申请号：EP12306354.7
申请日：2012-10-30
申请人： Pharnext
IPC分类号： A61K31/122 , A61K31/137 , A61K31/138 , A61K31/16 , A61K31/197 , A61K31/216 , A61K31/4164 , A61K31/42 , A61K31/437 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/519 , A61K31/53 , A61K31/55 , A61K31/7004 , A61P5/48
CPC分类号： A61K31/122 , A61K31/137 , A61K31/138 , A61K31/16 , A61K31/197 , A61K31/216 , A61K31/4164 , A61K31/42 , A61K31/422 , A61K31/437 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/519 , A61K31/53 , A61K31/55 , A61K31/7004 , A61K2300/00
摘要： The present invention relates to compositions and methods for controlling glycaemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes disease and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies of diabetes and related disorders, based on compositions controlling the blood glucose level.
摘要翻译： 本发明涉及组合物和用于在有需要的哺乳动物控制血糖的方法。 本发明涉及组合物和方法，用于糖尿病的疾病和相关病症的治疗。 更具体地，本发明涉及新的疗法或糖尿病的组合疗法和相关障碍，基于组合物控制血糖水平。
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2.发明公开New therapeutic approaches for treating neuroinflammatory conditions 有权Neue therapeutischeAnsätzezur Behandlung neuroinflammatorischer Erkrankungen
公开(公告)号：EP2735316A1
公开(公告)日：2014-05-28
申请号：EP14156048.2
申请日：2010-03-29
申请人： Pharnext
IPC分类号： A61K45/06 , A61K31/4365 , A61K31/137 , A61P25/28
CPC分类号： A61K31/137 , A61K31/4365 , A61K45/06 , A61K2300/00
摘要： The present invention relates to novel compositions which can be used for the treatment ofneuroinflammation, in particular in subjects having a neurodegenerative, autoimmune, infectious, toxic or traumatic disorder. More particularly, the invention relates to combined therapies for treating neuroinflammation. The invention also discloses new methods for treating neuroinflammation pathological conditions in a subject.
摘要翻译： 本发明涉及可用于治疗神经炎症的新型组合物，特别涉及具有神经退行性，自身免疫性，感染性，毒性或创伤性病症的受试者。 更具体地，本发明涉及用于治疗神经炎症的组合疗法。 本发明还公开了治疗受试者神经炎症病理状况的新方法。
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公开(公告)号：EP2727588A1
公开(公告)日：2014-05-07
申请号：EP13196461.1
申请日：2012-03-01
申请人： Pharnext
IPC分类号： A61K31/137 , A61K31/138 , A61K31/185 , A61K31/195 , A61K31/42 , A61K31/64 , A61P25/28 , A61K45/06 , A61K31/197 , A61K31/445 , A61K31/145 , A61K31/164 , A61K31/44
CPC分类号： A61K31/44 , A61K9/2004 , A61K31/137 , A61K31/138 , A61K31/145 , A61K31/164 , A61K31/185 , A61K31/195 , A61K31/197 , A61K31/42 , A61K31/428 , A61K31/445 , A61K31/64 , A61K45/06 , A61K2300/00
摘要： The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
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4.发明公开New therapeutic approaches for treating Charcot-Marie-Tooth disease 审中-公开Neue therapeutischeAnsätzezur Behandlung der Charcot-Marie-Tooth Krankheit
公开(公告)号：EP2065038A1
公开(公告)日：2009-06-03
申请号：EP07301614.9
申请日：2007-11-30
申请人： Pharnext
IPC分类号： A61K31/047 , A61K31/197 , A61K31/27 , A61K31/4178 , A61K31/485 , A61K31/567 , A61P25/28
CPC分类号： A61K31/485 , A61K9/0095 , A61K9/08 , A61K9/4866 , A61K31/047 , A61K31/197 , A61K31/7004
摘要： The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders. More particularly, the invention relates to combined therapies for treating said disease by decreasing PMP22 expression in a subject.
摘要翻译： 本发明涉及治疗Charcot-Marie-Tooth疾病和相关疾病的组合物和方法。 更具体地，本发明涉及通过降低受试者中的PMP22表达来治疗所述疾病的组合疗法。
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公开(公告)号：EP2823817B1
公开(公告)日：2017-06-21
申请号：EP14176796.2
申请日：2010-05-28
申请人： Pharnext
IPC分类号： A61K31/192 , A61K31/197 , A61K31/4164 , A61K31/4178 , A61K31/436 , A61K31/485 , A61K31/575 , A61K31/7004 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61K45/06
CPC分类号： A61K31/485 , A61K9/0053 , A61K31/047 , A61K31/192 , A61K31/195 , A61K31/197 , A61K31/4164 , A61K31/4178 , A61K31/436 , A61K31/439 , A61K31/555 , A61K31/567 , A61K31/575 , A61K31/7004 , A61K45/06 , A61K2300/00
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公开(公告)号：EP2735316B1
公开(公告)日：2016-10-05
申请号：EP14156048.2
申请日：2010-03-29
申请人： Pharnext
IPC分类号： A61K45/06 , A61K31/4365 , A61K31/137 , A61P25/28
CPC分类号： A61K31/137 , A61K31/4365 , A61K45/06 , A61K2300/00
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7.发明公开Therapeutic approaches for treating epilepsy and related disorders through reduction of epileptogenesis 审中-公开治疗方法治疗癫痫病及相关疾病通过减少癫痫
公开(公告)号：EP2705843A1
公开(公告)日：2014-03-12
申请号：EP12306064.2
申请日：2012-09-05
申请人： Pharnext
IPC分类号： A61K31/137 , A61K31/138 , A61K31/185 , A61K31/197 , A61K31/635 , A61K31/64 , A61K31/222 , A61K31/195 , A61K31/20 , A61K31/4015 , A61K31/4166 , A61K31/4192 , A61K31/515 , A61K31/53 , A61K31/55 , A61K31/5513 , A61K31/7048 , A61P25/08
CPC分类号： A61K31/185 , A61K31/137 , A61K31/138 , A61K31/195 , A61K31/197 , A61K31/20 , A61K31/222 , A61K31/4015 , A61K31/4166 , A61K31/4192 , A61K31/515 , A61K31/53 , A61K31/55 , A61K31/5513 , A61K31/635 , A61K31/64 , A61K31/7048 , A61K45/06 , A61K2300/00
摘要： The present invention relates to compositions and methods for the treatment of epilepsy and related disorders. More specifically, the present invention relates to novel combinatorial therapies of epilepsy and related disorders
摘要翻译： 本发明涉及组合物和方法，用于癫痫和相关疾病的治疗。 更具体地，本发明涉及癫痫新颖组合治疗和相关病症
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8.发明公开Therapeutic approaches for treating parkinson's disease 审中-公开TherapeutischeAnsätzezur Behandlung von Morbus帕金森病
公开(公告)号：EP2705842A1
公开(公告)日：2014-03-12
申请号：EP12306063.4
申请日：2012-09-05
申请人： Pharnext
IPC分类号： A61K31/137 , A61K31/138 , A61K31/155 , A61K31/185 , A61K31/192 , A61K31/197 , A61K31/198 , A61K31/24 , A61K31/403 , A61K31/4164 , A61K31/42 , A61K31/421 , A61K31/4402 , A61K31/4422 , A61K31/445 , A61K31/506 , A61K31/519
CPC分类号： A61K31/519 , A61K31/137 , A61K31/138 , A61K31/155 , A61K31/185 , A61K31/192 , A61K31/195 , A61K31/197 , A61K31/198 , A61K31/216 , A61K31/403 , A61K31/4164 , A61K31/42 , A61K31/421 , A61K31/44 , A61K31/4402 , A61K31/4422 , A61K31/445 , A61K31/506 , A61K45/06 , A61K31/24 , A61K2300/00 , A61K31/64 , A61K31/48 , A61K31/428 , A61K31/4045 , A61K31/485 , A61K31/135 , A61K31/165 , A61K31/5513 , A61K31/551 , A61K31/343 , A61K31/4525 , A61K31/13 , A61K31/27 , A61K31/353 , A61K31/55 , A61K31/416 , A61K31/4178 , A61K31/4458 , A61K31/505 , A61K31/4184
摘要： The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Parkinson's disease and related disorders targeting the alpha-synuclein aggregation network. In particular, the invention relates to compounds which, alone or in combination(s), can effectively protect neuronal cells from alpha-synuclein aggregates. The invention also relates to methods of producing a drug or a drug combination for treating Parkinson's disease and to methods of treating Parkinson's disease or a related disorder.
摘要翻译： 本发明涉及治疗帕金森病和相关疾病的组合物和方法。 更具体地，本发明涉及帕金森氏病的新组合疗法和靶向α-突触核蛋白聚集网络的相关病症。 特别地，本发明涉及单独或组合可以有效保护神经元细胞免受α-突触核蛋白聚集体的化合物。 本发明还涉及产生用于治疗帕金森病的药物或药物组合的方法以及治疗帕金森病或相关病症的方法。
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公开(公告)号：EP2727588B1
公开(公告)日：2018-08-29
申请号：EP13196461.1
申请日：2012-03-01
申请人： Pharnext
IPC分类号： A61K31/137 , A61K31/138 , A61K31/185 , A61K31/195 , A61K31/42 , A61K31/64 , A61P25/28 , A61K45/06 , A61K31/197 , A61K31/445 , A61K31/145 , A61K31/164 , A61K31/44 , A61K31/428 , A61K9/20
CPC分类号： A61K31/44 , A61K9/2004 , A61K31/137 , A61K31/138 , A61K31/145 , A61K31/164 , A61K31/185 , A61K31/195 , A61K31/197 , A61K31/42 , A61K31/428 , A61K31/445 , A61K31/64 , A61K45/06 , A61K2300/00
摘要： The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ² toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
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公开(公告)号：EP2796132A1
公开(公告)日：2014-10-29
申请号：EP13196468.6
申请日：2012-03-01
申请人： Pharnext
IPC分类号： A61K31/137 , A61K31/138 , A61K31/185 , A61K31/195 , A61K31/42 , A61K31/64 , A61P25/16 , A61P25/28 , A61P25/00
CPC分类号： A61K31/44 , A61K9/2004 , A61K31/137 , A61K31/138 , A61K31/145 , A61K31/164 , A61K31/185 , A61K31/195 , A61K31/197 , A61K31/42 , A61K31/428 , A61K31/445 , A61K31/64 , A61K45/06 , A61K2300/00
摘要： The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
摘要翻译： 本发明涉及用于治疗与谷氨酸兴奋毒性和淀粉样蛋白β毒性相关的神经障碍的组合和方法。 更具体地，本发明涉及多发性硬化，阿尔茨海默氏病，阿尔茨海默氏病相关病症的新的组合治疗，肌萎缩性侧索硬化，帕金森氏病，亨廷顿氏病，神经性疼痛，酒精性神经病变，酒精中毒或酒精戒断，或脊髓损伤，基于 对巴氯芬和阿坎酸组合。
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