发明公开
- 专利标题： TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS
- 专利标题（中）： 癌的HSP90炎症化合物的治疗
-
申请号： EP12735423.1申请日： 2012-07-09
-
公开(公告)号： EP2729144A2公开(公告)日： 2014-05-14
- 发明人: EL-HARIRY, Iman , PROIA, David , VUKOVIC, Vojo
- 申请人： Synta Pharmaceuticals Corp.
- 申请人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 代理机构： Potter Clarkson LLP
- 优先权： US201161505322P 20110707; US201161549941P 20111021; US201261623762P 20120413
- 国际公布： WO2013006864 20130110
- 主分类号： A61K31/4196
- IPC分类号： A61K31/4196 ; A61K31/4439 ; A61P35/00
摘要：
Methods of treating cancer with a compound of formulae (I) or (la) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of formulae (I) or (la). Further provided are methods of treating non-small cell lung cancer with a mutation in ALK with a compound of formulae (I) or (la); a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables structural formulae are defined herein.
信息查询
