发明公开
- 专利标题: BAX AGONIST, COMPOSITIONS, AND METHODS RELATED THERETO
- 专利标题(中): BAX激动剂,组合物和相关方法
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申请号: EP12825339.0申请日: 2012-08-17
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公开(公告)号: EP2744775A1公开(公告)日: 2014-06-25
- 发明人: DENG, Xingming , ZHOU, Jia , DING, Chunyong
- 申请人: Emory University , Board of Regents of the University of Texas System
- 申请人地址: 1599 Clifton Rd. NE 4th Floor Atlanta, GA 30322 US
- 专利权人: Emory University,Board of Regents of the University of Texas System
- 当前专利权人: Emory University,Board of Regents of the University of Texas System
- 当前专利权人地址: 1599 Clifton Rd. NE 4th Floor Atlanta, GA 30322 US
- 代理机构: Lau, Sarah Jane
- 优先权: US201161525249P 20110819; US201261648887P 20120518
- 国际公布: WO2013028543 20130228
- 主分类号: C07C205/25
- IPC分类号: C07C205/25 ; C07C205/35 ; C07C211/48 ; C07C211/52 ; C07C215/88 ; C07C217/54 ; C07C217/94 ; C07C233/07 ; C07C233/18 ; C07C271/16 ; C07C309/65 ; A61K31/05 ; A61K31/085 ; A61K31/136 ; A61K31/138 ; A61K31/164 ; A61K31/167 ; A61K31/27 ; A61K31/404 ; A61K31/4425
摘要:
The disclosure relates to BAX activators and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.
公开/授权文献
- EP2744775B1 BAX AGONIST, COMPOSITIONS, AND METHODS RELATED THERETO 公开/授权日:2018-03-07
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