发明公开
- 专利标题: IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES
- 专利标题(中): 离子标签合成寡核糖核苷酸
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申请号: EP12824951申请日: 2012-08-23
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公开(公告)号: EP2748176A4公开(公告)日: 2015-09-16
- 发明人: DAMHA MASAD J , HASSLER MATTHEW , CHAN TAK-HANG , REDDY N MALLIKARJUNA , DONGA ROBERT ALEXANDER
- 申请人: UNIV MCGILL , UNIV HONG KONG POLYTECHNIC
- 专利权人: UNIV MCGILL,UNIV HONG KONG POLYTECHNIC
- 当前专利权人: UNIV MCGILL,UNIV HONG KONG POLYTECHNIC
- 优先权: US201261602373 2012-02-23
- 主分类号: C07H21/00
- IPC分类号: C07H21/00 ; C07D233/60 ; C07F9/54 ; C07H19/02 ; C07H21/02 ; C40B70/00 ; C40B80/00
摘要:
The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II) processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.
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