发明公开
EP2753312A1 USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES 有权
芳香酶抑制剂的用于治疗性腺功能减退症和相关疾病的

  • 专利标题: USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES
  • 专利标题(中): 芳香酶抑制剂的用于治疗性腺功能减退症和相关疾病的
  • 申请号: EP12758965.3
    申请日: 2012-09-06
  • 公开(公告)号: EP2753312A1
    公开(公告)日: 2014-07-16
  • 发明人: TAYLOR, AnnKLICKSTEIN, Lloyd B.
  • 申请人: Novartis AG
  • 申请人地址: Lichtstrasse 35 4056 Basel CH
  • 专利权人: Novartis AG
  • 当前专利权人: Novartis AG
  • 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
  • 代理机构: Larbig, Karen Dorothee
  • 优先权: US201161532459P 20110908; US201261638588P 20120426
  • 国际公布: WO2013036562 20130314
  • 主分类号: A61K9/48
  • IPC分类号: A61K9/48 A61K31/4196 A61P5/26 A61P15/08
USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES
摘要:
This invention relates to a method of increasing testosterone levels and treating hypogonadism and related diseases with the aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile. The present invention further relates to a method of increasing testosterone levels and treating hypogonadism and related diseases with the aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile in a particular dosing regimen. The invention also relates to pharmaceutical compositions comprising said aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, optionally in combination with other active ingredients. Furthermore, the present invention relates to kits comprising said pharmaceutical compositions together with instructions how to administer them.
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