发明公开
EP2753312A1 USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES
有权
芳香酶抑制剂的用于治疗性腺功能减退症和相关疾病的
- 专利标题: USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES
- 专利标题(中): 芳香酶抑制剂的用于治疗性腺功能减退症和相关疾病的
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申请号: EP12758965.3申请日: 2012-09-06
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公开(公告)号: EP2753312A1公开(公告)日: 2014-07-16
- 发明人: TAYLOR, Ann , KLICKSTEIN, Lloyd B.
- 申请人: Novartis AG
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Larbig, Karen Dorothee
- 优先权: US201161532459P 20110908; US201261638588P 20120426
- 国际公布: WO2013036562 20130314
- 主分类号: A61K9/48
- IPC分类号: A61K9/48 ; A61K31/4196 ; A61P5/26 ; A61P15/08
摘要:
This invention relates to a method of increasing testosterone levels and treating hypogonadism and related diseases with the aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile. The present invention further relates to a method of increasing testosterone levels and treating hypogonadism and related diseases with the aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile in a particular dosing regimen. The invention also relates to pharmaceutical compositions comprising said aromatase inhibitor 4,4'-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, optionally in combination with other active ingredients. Furthermore, the present invention relates to kits comprising said pharmaceutical compositions together with instructions how to administer them.
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