发明公开
- 专利标题: RECOMBINANT PHAGE AND METHODS
- 专利标题(中): REKOMBINANTER PHAGE UND VERFAHREN
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申请号: EP12835856申请日: 2012-09-26
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公开(公告)号: EP2761014A4公开(公告)日: 2015-04-22
- 发明人: LU TIMOTHY KUAN TA , KOERIS MICHAEL SANDOR , CHEVALIER BRETT SMITH , HOLDER JASON WYATT , MCKENZIE GREGORY JOHN , BROWNELL DANIEL ROBERT
- 申请人: SAMPLE6 TECHNOLOGIES INC
- 专利权人: SAMPLE6 TECHNOLOGIES INC
- 当前专利权人: SAMPLE6 TECHNOLOGIES INC
- 优先权: US201161539454 2011-09-26; US201161549743 2011-10-20; US201261642691 2012-05-04
- 主分类号: C12P19/34
- IPC分类号: C12P19/34
摘要:
This disclosure provided methods of cloning a phage genome. Also provided are methods of making a recombinant phage genome. In some embodiments the phage genome is engineered to comprise a heterologous nucleic acid sequence, for example a sequence comprising an open reading frame. In some embodiments the phage genome is cloned in a yeast artificial chromosome. Recombinant phage genomes and recombinant phage are also provided. In some embodiments the methods are high throughput methods such as methods of making a plurality of recombinant phage genomes or recombinant phage. Collections of recombinant phage genomes and recombinant phage are also provided.
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