发明授权
- 专利标题: MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS
- 专利标题(中): FOR抑制细胞凋亡的大环化合物抑制剂
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申请号: EP12787341.2申请日: 2012-11-09
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公开(公告)号: EP2776409B1公开(公告)日: 2016-02-03
- 发明人: SEIGAL, Benjamin, Adam , TERRETT, Nicholas , CARTER, Percy, H. , BORZILLERI, Robert, M. , ZHANG, Yong , MILLER, Michael, M.
- 申请人: Ensemble Therapeutics Corporation , Bristol-Myers Squibb Company
- 申请人地址: 99 Erie Street Cambridge MA 02139 US
- 专利权人: Ensemble Therapeutics Corporation,Bristol-Myers Squibb Company
- 当前专利权人: Ensemble Therapeutics Corporation,Bristol-Myers Squibb Company
- 当前专利权人地址: 99 Erie Street Cambridge MA 02139 US
- 代理机构: Cole, William Gwyn
- 优先权: US201161557823P 20111109
- 国际公布: WO2013071035 20130516
- 主分类号: C07D249/04
- IPC分类号: C07D249/04 ; A61P35/00
摘要:
The invention relates generally to macrocyclic compounds and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of inhibitors of apoptosis (IAPs) and/or are useful in the treatment of medical conditions, such as cancer.
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