发明公开
- 专利标题: ARYL DIHYDROPYRIDINONES AND PIPERIDINONES AS MGAT2 INHIBITORS
- 专利标题(中): 芳基和二氢吡啶哌啶酮ALS抑制剂MGAT2
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申请号: EP12821212.3申请日: 2012-11-30
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公开(公告)号: EP2785693A1公开(公告)日: 2014-10-08
- 发明人: TURDI, Huji , HANGELAND, Jon J. , LAWRENCE, R. Michael , CHENG, Dong , AHMAD, Saleem , MENG, Wei , BRIGANCE, Robert Paul , DEVASTHALE, Pratik , ZHAO, Guohua
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: Post Office Box 4000 Route 206 and Province Line Road Princeton, NJ 08543-4000 US
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: Post Office Box 4000 Route 206 and Province Line Road Princeton, NJ 08543-4000 US
- 代理机构: Beacham, Annabel Rose
- 优先权: US201161566039P 20111202; US201213688584 20121129
- 国际公布: WO2013082345 20130606
- 主分类号: C07D211/86
- IPC分类号: C07D211/86 ; C07D211/90 ; C07D401/04 ; C07D401/10 ; C07D401/12 ; C07D401/14 ; C07D407/14 ; C07D413/04 ; C07D413/12 ; C07D417/04 ; C07D417/14 ; C07F9/40 ; A61K31/4418 ; A61K31/4427 ; A61P3/00
摘要:
The present invention provides compounds of Formula (I), or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
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