发明公开
EP2789617A1 Method of preparation of Enantiomers of spiro-oxindole compounds
有权
Verfahren zur Herstellung von Enantiomere aus Spiro-Oxindol-Verbindungen
- 专利标题： Method of preparation of Enantiomers of spiro-oxindole compounds
- 专利标题（中）： Verfahren zur Herstellung von Enantiomere aus Spiro-Oxindol-Verbindungen
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申请号： EP14000690.9申请日： 2010-06-28
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公开(公告)号： EP2789617A1公开(公告)日： 2014-10-15
- 发明人: Chafeev, Mikhail , Fu, Jianmin , Cadieux, Jean-Jacques
- 申请人： Xenon Pharmaceuticals Inc.
- 申请人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser
- 优先权： US221424P 20090629
- 主分类号： C07D491/22
- IPC分类号： C07D491/22 ; A61K31/404 ; A61P29/00
摘要：
This invention is directed to a method of preparation of the (S)-enantiomer of the compound of formula (I):
This (S)-enantiomer is useful for the treatment of diseases or conditions, such as pain, which are ameliorated or alleviated by the modulation of voltage-gated sodium channels.
This (S)-enantiomer is useful for the treatment of diseases or conditions, such as pain, which are ameliorated or alleviated by the modulation of voltage-gated sodium channels.
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