发明公开
- 专利标题： PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS
- 专利标题（中）： 吡咯烷酮 - 吡咯烷酮
-
申请号： EP12813423.6申请日： 2012-12-20
-
公开(公告)号： EP2794597A1公开(公告)日： 2014-10-29
- 发明人: COURTNEY, Steve , YARNOLD, Chris , FLANAGAN, Stuart , BRACE, Gareth , BARKER. John , ICHIHARA, Osamu , GADOULEAU, Elise , RICHARDSON, Anthony , KONDO, Takashi , IMAGAWA, Akira , NAKATANI, Shingo , SUZUKI, Ryo , KOUYAMA, Sho
- 申请人： ONO Pharmaceutical Co., Ltd.
- 申请人地址： 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi, Osaka 541-8526 JP
- 专利权人： ONO Pharmaceutical Co., Ltd.
- 当前专利权人： ONO Pharmaceutical Co., Ltd.
- 当前专利权人地址： 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi, Osaka 541-8526 JP
- 代理机构： Wright, Simon Mark
- 优先权： GB201122139 20111221; GB201217290 20120927
- 国际公布： WO2013093484 20130627
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D471/04 ; C07D487/04 ; A61K31/437 ; A61K31/519 ; A61P9/00
摘要：
The present invention provides compounds of the general formula (I), their salts and N- oxides, and solvates and prodrugs thereof (wherein the characters are as defined in the description). The compounds of the general formula (I) are inhibitors of Factor XIa, so that they are useful in the prevention of and/or therapy for thromboembolic diseases.
公开/授权文献
信息查询
