发明公开
EP2794620A4 BODIPY STRUCTURE FLUORESCENCE PROBES FOR DIVERSE BIOLOGICAL APPLICATIONS
有权
FLUORESZENZSONDEN MIT BODIPY-STRUKTURFÜRVERSCHIEDENE BIOLOGISCHE ANWENDUNGEN
- 专利标题： BODIPY STRUCTURE FLUORESCENCE PROBES FOR DIVERSE BIOLOGICAL APPLICATIONS
- 专利标题（中）： FLUORESZENZSONDEN MIT BODIPY-STRUKTURFÜRVERSCHIEDENE BIOLOGISCHE ANWENDUNGEN
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申请号： EP12859000申请日： 2012-12-20
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公开(公告)号： EP2794620A4公开(公告)日： 2015-09-02
- 发明人: CHANG YOUNG-TAE , LEE SUNG CHAN , KANG NAM-YOUNG , YUN SEONG WOOK , LEONG CHERYL KIT MUN , HA HYUNG HO
- 申请人： UNIV SINGAPORE , AGENCY SCIENCE TECH & RES
- 专利权人： UNIV SINGAPORE,AGENCY SCIENCE TECH & RES
- 当前专利权人： UNIV SINGAPORE,AGENCY SCIENCE TECH & RES
- 优先权： US201161579461 2011-12-22
- 主分类号： C07F5/02
- IPC分类号： C07F5/02 ; G01N33/533
摘要：
The present invention is directed to a fluorescence compound represented by structural Formula (I), with specificity to neural stem cells: (I), or a pharmaceutically acceptable salt thereof. The variables for structural Formula (I) are defined herein. Also described are methods for detection of beta cells, pancreatic islets and microglia cells, comprising using a compound of structural Formula (I) or pharmaceutically acceptable salts thereof. Compounds of structural Formula (I) can also differentiate healthy pancreatic islet cells from diabetic pancreatic islet cells.
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