发明公开
- 专利标题： Pyrimidinones as PI3K inhibitors
- 专利标题（中）： 嘧啶酮PI3K-Hemmer
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申请号： EP14169702.9申请日： 2010-06-28
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公开(公告)号： EP2845856A1公开(公告)日： 2015-03-11
- 发明人: Li, Yun-Long , Metcalf, Brian, W. , Combs, Andrew, P.
- 申请人： Incyte Corporation
- 申请人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 专利权人： Incyte Corporation
- 当前专利权人： Incyte Corporation
- 当前专利权人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US221160P 20090629; US259765P 20091110
- 主分类号： C07D473/34
- IPC分类号： C07D473/34 ; C07D513/04 ; A61K31/52 ; A61P29/00 ; A61P37/00
摘要：
The present invention provides pyrimidinones that modulate activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
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