发明授权
- 专利标题： ALIPHATIC SPIROLACTAM CGRP RECEPTOR ANTAGONISTS
- 专利标题（中）： 脂肪醇螺旋藻CGRP受体拮抗剂
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申请号： EP13788067.0申请日： 2013-05-03
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公开(公告)号： EP2846798B1公开(公告)日： 2018-04-04
- 发明人: BELL, Ian, M. , FRALEY, Mark , BIFTU, Tesfaye , ZHU, Cheng , NAIR, Anilkumar , MITCHELL, Helen
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Jaap, David Robert
- 优先权： US201261644628P 20120509
- 国际公布： WO2013169574 20131114
- 主分类号： C07D471/20
- IPC分类号： C07D471/20 ; A61K31/4523 ; A61K31/45 ; A61K31/451 ; A61P25/06
摘要：
The present invention is directed to aliphatic spirolactam derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical\compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
公开/授权文献
- EP2846798A2 ALIPHATIC SPIROLACTAM CGRP RECEPTOR ANTAGONISTS 公开/授权日：2015-03-18
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