-
公开(公告)号：EP4452938A1
公开(公告)日：2024-10-30
申请号：EP22908929.7
申请日：2022-12-23
申请人： Psylo Pty Ltd
IPC分类号： C07D209/16 , A61K31/4045 , A61P25/00 , A61P25/02 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P25/30 , C07D405/12
-
公开(公告)号：EP4452937A1
公开(公告)日：2024-10-30
申请号：EP22908928.9
申请日：2022-12-23
申请人： Psylo Pty Ltd
IPC分类号： C07D209/16 , A61K31/4045 , A61K31/423 , A61P25/00 , A61P25/02 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P25/30 , C07D491/048 , C07D491/04
-
公开(公告)号：EP4433453A1
公开(公告)日：2024-09-25
申请号：EP22839542.2
申请日：2022-11-17
发明人： CHAPMAN, Mark , DAVIDSON, James , DAVIES, Nicholas, Gareth Morse , GERLACH, Aaron , GRAHAM, Christopher, John , LEBRETON, Sylvain , LI, Ronghua , MA, Nina , MECHIN, Ingrid , MOWREY, David , NAGARAJAN, Karthigeyan , NAIR, Anil , NORCROSS, Roger David , REDONDO PENA, Roger Lluis , SAFAROVA, Alena , SMRCINA, Martin
IPC分类号： C07D213/36 , C07D213/56 , C07D213/64 , C07D213/84 , C07D401/04 , C07D401/12 , C07D405/12 , C07D405/14 , C07D413/04 , C07D493/08 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28
CPC分类号： C07D405/14 , C07D401/04 , C07D213/84 , C07D213/64 , C07D405/12 , C07D213/56 , C07D213/36 , C07D413/04 , C07D401/12 , C07D493/08 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/04 , A61P25/06 , A61P25/08
-
4.发明公开
公开(公告)号：EP4433090A1
公开(公告)日：2024-09-25
申请号：EP22839091.0
申请日：2022-11-21
发明人： PRAVEEN, Kavita , COPPOLA, Giovanni , BARAS, Aris
CPC分类号： A61K45/06 , A61K31/713 , A61P25/06 , A61P25/04 , C12Q1/6883 , C12Q2600/15620130101 , C12N9/22 , C12N15/1138 , A61K31/7105
-
公开(公告)号：EP4384208A1
公开(公告)日：2024-06-19
申请号：EP22856813.5
申请日：2022-08-11
申请人： Aeon Biopharma, Inc.
CPC分类号： Y02A50/30 , A61P25/06 , A61K9/0019 , A61K47/02 , A61K38/4893 , C12Y304/24069
-
6.发明授权
-
公开(公告)号：EP4299127A3
公开(公告)日：2024-05-15
申请号：EP23209087.8
申请日：2017-07-28
IPC分类号： A61K31/64 , A61K31/17 , A61K31/18 , A61P25/00 , A61K31/4045 , A61K31/7076 , A61K38/48 , A61K38/49 , A61K45/06 , A61P25/06
CPC分类号： A61P25/00 , A61K45/06 , A61K31/7076 , A61K38/49 , C12Y304/21069 , A61K31/64 , A61P25/06 , A61K31/4045 , A61K38/482 , A61K38/4893 , C12Y304/21068 , C12Y304/24069
摘要： A method of treating or preventing adverse outcomes associated with tissue plasminogen activator (tPA) administration, cerebral edema-related side effects, cerebral edema associated with radiation therapy, or migraine headaches by administering an effective amount of a SUR1-TRPM4 channel inhibitor, such as glyburide, and optionally the coadministration of a second therapeutically active agent, to a subject in need thereof. Adverse outcomes associated with tPA include cerebral hemorrhage, cerebral edema, physical impairment or death. The administration of the SUR1-TRPM4 channel inhibitors occurs prior to the radiation therapy, during the radiation therapy, after the radiation therapy, or combinations thereof. The SUR1-TRPM4 channel inhibitor is administered prior to surgical excision of a brain tumor, CAR-T therapy, or administration of flutarabine. Alternatively, or in addition, the SUR1-TRPM4 channel inhibitor is administered prior the onset of the cerebral edema-related side effect.
-
公开(公告)号：EP4337182A1
公开(公告)日：2024-03-20
申请号：EP22728723.2
申请日：2022-05-16
发明人： MEHRA, Raj , WHITAKER, Timothy
-
公开(公告)号：EP4317158A1
公开(公告)日：2024-02-07
申请号：EP22778836.1
申请日：2022-03-28
发明人： WEN, Chuanjun , ZOU, Junyi , SUN, Fenyong
IPC分类号： C07D471/04 , A61P29/00 , A61P25/04 , A61P1/16 , A61P35/00 , A61P9/10 , A61P9/00 , A61P25/08 , A61P25/06 , A61K31/4745
摘要： The present invention discloses a quinone compound and pharmaceutical use thereof. The quinone compound has a chemical structure of a general formula (I). The quinone compound has a phamaceutical value and a unique analgesic effect, inhibits inflammation and inhibits invasion and growth of tumor cells. The quinone compound can be used for preparing analgesic drugs, anti-tumor drugs, anti-inflammatory drugs, drugs for treating autoimmune diseases and the like.
-
公开(公告)号：EP4317153A1
公开(公告)日：2024-02-07
申请号：EP22781270.8
申请日：2022-03-31
IPC分类号： C07D405/14 , A61K9/20 , A61K31/136 , A61K31/4439 , A61K31/501 , A61K45/00 , A61P9/06 , A61P19/10 , A61P21/02 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/24 , A61P29/00 , A61P43/00 , C07D409/14 , C07D417/14 , C07D487/04 , C07D495/04 , C07D495/14 , C07D513/04
摘要： A drug is provided, which containing, as an active ingredient, a compound having ABHD6 inhibitory activity in prevention and/or treatment of a disease associated with ABHD6. A compound represented by general formula (I-A) or a pharmaceutically acceptable salt thereof has ABHD6 inhibitory activity and therefore is useful as a pharmaceutical ingredient having potent ABHD6 inhibitory activity in the prevention and/or treatment of a disease associated with ABHD6:
in which all symbols represent the same meaning as the symbols described in the specification.
-
-
-
-
-
-
-
-
-
搜索结果
1440 条记录 (耗时 0.021 秒)
