发明公开
EP2846807A4 METHOD AND COMPOUNDS FOR INHIBITING THE MCM COMPLEX AND THEIR APPLICATION IN CANCER TREATMENT
审中-公开
抑制MCM配合物的方法，化合物，以及它们在癌症治疗
- 专利标题： METHOD AND COMPOUNDS FOR INHIBITING THE MCM COMPLEX AND THEIR APPLICATION IN CANCER TREATMENT
- 专利标题（中）： 抑制MCM配合物的方法，化合物，以及它们在癌症治疗
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申请号： EP13787939申请日： 2013-05-09
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公开(公告)号： EP2846807A4公开(公告)日： 2016-07-27
- 发明人: LIANG CHUN , JIANG ZHIHONG , WANG ZIYI , YU ZHILING , WANG JINGRONG , BAI LIPING
- 申请人： UNIV HONG KONG SCIENCE & TECHN , UNIV HONG KONG BAPTIST , UNIV MACAU SCI & TECH
- 专利权人： UNIV HONG KONG SCIENCE & TECHN,UNIV HONG KONG BAPTIST,UNIV MACAU SCI & TECH
- 当前专利权人： UNIV HONG KONG SCIENCE & TECHN,UNIV HONG KONG BAPTIST,UNIV MACAU SCI & TECH
- 优先权： US201261644442 2012-05-09
- 主分类号： A61P35/00
- IPC分类号： A61P35/00 ; A61K31/585 ; A61K31/7048
摘要：
A method for treating cancer by using an agent which is capable of inhibiting the functionality of the MCM complex, a heterohexameric ring formed from six subunits, in the process of DNA replication and a method of screening for such agents by detecting the locations and functions of the MCM subunits, such as hMcm2 and hMcm6, in cells treated with candidate compounds.
信息查询
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
