专利检索 ap:("UNIV HONG KONG SCIENCE & TECHN" OR "UNIV HONG KONG BAPTIST" OR "UNIV MACAU SCI & TECH") AND inv:"LIANG CHUN" 第 1 页

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发明公开
METHOD AND COMPOUNDS FOR INHIBITING THE MCM COMPLEX AND THEIR APPLICATION IN CANCER TREATMENT 审中-公开
标题翻译：抑制MCM配合物的方法，化合物，以及它们在癌症治疗

公开(公告)号：EP2846807A4

公开(公告)日：2016-07-27

申请号：EP13787939

申请日：2013-05-09

申请人： UNIV HONG KONG SCIENCE & TECHN , UNIV HONG KONG BAPTIST , UNIV MACAU SCI & TECH

发明人： LIANG CHUN , JIANG ZHIHONG , WANG ZIYI , YU ZHILING , WANG JINGRONG , BAI LIPING

IPC分类号： A61P35/00 , A61K31/585 , A61K31/7048

CPC分类号： A61K31/7048 , A61K31/585 , G01N33/5011 , G01N33/5044 , G01N33/574 , G01N2458/00 , G01N2500/10

摘要： A method for treating cancer by using an agent which is capable of inhibiting the functionality of the MCM complex, a heterohexameric ring formed from six subunits, in the process of DNA replication and a method of screening for such agents by detecting the locations and functions of the MCM subunits, such as hMcm2 and hMcm6, in cells treated with candidate compounds.