发明公开
- 专利标题： SUBSTITUTED PYRROLOPYRIMIDINES
- 专利标题（中）： 取代的吡咯
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申请号： EP13723164.3申请日： 2013-05-17
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公开(公告)号： EP2852593A1公开(公告)日： 2015-04-01
- 发明人: KLAR, Ulrich , KETTSCHAU, Georg , SÜLZLE, Detlev , PÜHLER,Florian , KOSEMUND, Dirk , LIENAU, Philip , BÖMER, Ulf , WORTMANN, Lars
- 申请人： Bayer Pharma Aktiengesellschaft
- 申请人地址： Müllerstrasse 178 13353 Berlin DE
- 专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人： Bayer Pharma Aktiengesellschaft
- 当前专利权人地址： Müllerstrasse 178 13353 Berlin DE
- 代理机构： BIP Patents
- 优先权： EP12168671 20120521; EP13153905 20130204
- 国际公布： WO2013174743 20131128
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P37/00
摘要：
The present invention relates to substituted pyrrolopyrimidine compounds general formula I : in which A, X, R
1 , R
2 , m and n are as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
1 , R
2 , m and n are as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
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