发明公开
EP2852619A1 TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE
审中-公开
易位不是化学天然物质,通过对炭疽保护抗原孔隙
- 专利标题: TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE
- 专利标题(中): 易位不是化学天然物质,通过对炭疽保护抗原孔隙
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申请号: EP13793070.7申请日: 2013-05-21
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公开(公告)号: EP2852619A1公开(公告)日: 2015-04-01
- 发明人: LIAO, Xiaoli , RABIDEAU, Amy, E. , PENTELUTE, Bradley, L. , LING, Jingjing , AKÇAY, Gizem
- 申请人: Massachusetts Institute of Technology
- 申请人地址: 77 Massachusetts Avenue Cambridge, MA 02139 US
- 专利权人: Massachusetts Institute of Technology
- 当前专利权人: Massachusetts Institute of Technology
- 当前专利权人地址: 77 Massachusetts Avenue Cambridge, MA 02139 US
- 代理机构: Potter Clarkson LLP
- 优先权: US201261649421P 20120521; US201261649866P 20120521
- 国际公布: WO2013177231 20131128
- 主分类号: C07K19/00
- IPC分类号: C07K19/00 ; C07K1/107 ; C07K1/36 ; C07K7/06 ; C07K17/06 ; C12N15/12 ; C12N15/63 ; C12P21/04 ; A61K38/03 ; A61K38/17 ; B82Y5/00
摘要:
Disclosed is a new approach for delivering compounds and drugs to the cytosol of living cells through the use of engineered protein transporters. The engineered protein transporters include a pore and a pore specific delivery protein, wherein a reagent such as a drug is attached to one or more of the engineered protein transporters.
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