A device for transdermal and/or intradermal transport that can be connected to two electrodes, wherein one of the electrodes is configured for containing an active principle to be administered via transdermal and/or intradermal route. The device comprises a wave generator configured for generating a driving signal to be sent to the electrodes. In one embodiment, the driving signal comprises a plurality of packets grouped in trains of packets (Tr) and in groups of trains (TG), wherein each packet consists of a unidirectional signal that results from the combination of a modulating signal and a carrier signal, wherein each train of packets (Tr) consists of a series of packets, and wherein each group of trains (TG) comprises a series of trains of packets (Tr). In addition, the wave generator can be configured for reversing the polarity of the trains of packets (Tr) after a given time interval.