发明公开
EP2861720A1 GROWTH FACTOR COCKTAIL TO ENHANCE OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL CELLS
审中-公开
WACHSTUMSFAKTOR-COCKTAIL ZUR VERBESSERUNG DER OSTEOGENEN DIFFERENZIERUNG MESENCHYMALER ZELLEN
- 专利标题： GROWTH FACTOR COCKTAIL TO ENHANCE OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL CELLS
- 专利标题（中）： WACHSTUMSFAKTOR-COCKTAIL ZUR VERBESSERUNG DER OSTEOGENEN DIFFERENZIERUNG MESENCHYMALER ZELLEN
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申请号： EP13732409.1申请日： 2013-06-19
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公开(公告)号： EP2861720A1公开(公告)日： 2015-04-22
- 发明人: CHEN, Christopher , LUYTEN, Frank , EYCKMANS, Jeroen , SCHROOTEN, Jan , ROBERTS, Scott
- 申请人： University Of Pennsylvania , Katholieke Universiteit Leuven
- 申请人地址： 3160 Chestnut Street Suite 200 Philadelphia, PA 19104-6283 US
- 专利权人： University Of Pennsylvania,Katholieke Universiteit Leuven
- 当前专利权人： University Of Pennsylvania,Katholieke Universiteit Leuven
- 当前专利权人地址： 3160 Chestnut Street Suite 200 Philadelphia, PA 19104-6283 US
- 代理机构： LC Patents
- 优先权： US201261661448P 20120619; GB201213571 20120731
- 国际公布： WO2013189975 20131227
- 主分类号： C12N5/071
- IPC分类号： C12N5/071
摘要：
The present invention relates to methods and compositions for osteogenic differentiation of human periosteum derived cells, in particular using a growth medium containing a specific combination of growth factors and formulations thereof. The invention also relates to the differentiated cells and cell populations, as well as further products comprising such cells and uses thereof in bone therapy.
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