发明公开
EP2865669A1 NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF
审中-公开
新的雷ABAMIDE产物，其制备方法及其用途
- 专利标题： NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF
- 专利标题（中）： 新的雷ABAMIDE产物，其制备方法及其用途
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申请号： EP13809037.8申请日： 2013-06-26
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公开(公告)号： EP2865669A1公开(公告)日： 2015-04-29
- 发明人: CHO, Eui-Hwan , CHOI, Sung Ju , LEE, Sung Woo , SHIN, Hee Jong , KWON, Ho Seok , LEE, Jae Woong , JOO, Jeong Ho , KIM, Hyun Tae , SONG, Woo Heon , YOON, Jong Bae , PARK, Ki Seok , PARK, Ho Joon , NAM, Ho Tae
- 申请人： Samjin Pharmaceutical Co., Ltd. , Astech. Co., Ltd.
- 申请人地址： 338-8 Seogyo-dong Mapo-gu Seoul 121-836 KR
- 专利权人： Samjin Pharmaceutical Co., Ltd.,Astech. Co., Ltd.
- 当前专利权人： Samjin Pharmaceutical Co., Ltd.,Astech. Co., Ltd.
- 当前专利权人地址： 338-8 Seogyo-dong Mapo-gu Seoul 121-836 KR
- 代理机构： Asensio, Raffaella Consuelo
- 优先权： KR20120068394 20120626
- 国际公布： WO2014003424 20140103
- 主分类号： C07D215/227
- IPC分类号： C07D215/227 ; C07D413/12 ; A61K31/4704 ; A61P1/04
摘要：
Disclosed are a novel rebamipide prodrug, a method for preparing the same, and use thereof. Also, a pharmaceutical composition comprising the novel rebamipide prodrug as an active ingredient is provided. The rebamipide prodrug is increased 25-fold in absorption rate compared to rebamipide itself, and can be applied to the prophylaxis or therapy of gastric ulcer, acute gastritis, chronic gastritis, xerophthalmia, cancer, osteoarthritis, rheumatoid arthritis, or obesity.
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