发明公开
- 专利标题: INACTIVATION OF A PRODUCTION STRAIN USING A FATTY ACID
- 专利标题(中): 禁用生产菌株USING A FATTY
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申请号: EP13732582.5申请日: 2013-07-02
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公开(公告)号: EP2870256A1公开(公告)日: 2015-05-13
- 发明人: JENSEN, Helene, Munthe , ELLEGAARD, Martin , JAKOBSEN, Sune
- 申请人: Novozymes A/S
- 申请人地址: Krogshøjvej 36 2880 Bagsværd DK
- 专利权人: Novozymes A/S
- 当前专利权人: Novozymes A/S
- 当前专利权人地址: Krogshøjvej 36 2880 Bagsværd DK
- 优先权: EP12175293 20120706
- 国际公布: WO2014006040 20140109
- 主分类号: C12P21/00
- IPC分类号: C12P21/00 ; C12P21/02 ; C12N1/00 ; A01N37/02 ; C12N1/14
摘要:
A method of inactivating the microbial host cell in a fermentation broth comprising an enzyme of interest and the microbial host cell producing the enzyme of interest comprising: a) Adding a fatty acid having a chain length of C4-C12 to the fermentation broth; and b) Mixing the fermentation broth for a sufficient period of time until the microbial host cell is inactivated.
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