发明公开
- 专利标题： FUSED HETEROCYCLIC COMPOUNDS AS SELECTIVE BMP INHIBITORS
- 专利标题（中）： 简明杂环化合物作为选择性抑制剂，BMP
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申请号： EP13840866申请日： 2013-03-15
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公开(公告)号： EP2900238A4公开(公告)日： 2016-04-06
- 发明人: HOPKINS COREY R , HONG CHARLES C , LINDSLEY CRAIG W , ENGERS DARREN W
- 申请人： UNIV VANDERBILT
- 专利权人： UNIV VANDERBILT
- 当前专利权人： UNIV VANDERBILT
- 优先权： US201261707661 2012-09-28
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61K31/438 ; A61K31/4709 ; A61K31/5025 ; A61K31/519 ; A61P1/16 ; A61P7/02 ; A61P9/00 ; A61P17/00 ; A61P29/00 ; A61P35/00 ; C07D487/04 ; C07D519/00
摘要：
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
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