发明公开
EP2946014A2 SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES
审中-公开
信号传感器 - 多晶硅ZURVERÄNDERUNGZELLULÄRERPHÄNOTYPEN
- 专利标题: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES
- 专利标题(中): 信号传感器 - 多晶硅ZURVERÄNDERUNGZELLULÄRERPHÄNOTYPEN
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申请号: EP13779972.2申请日: 2013-09-30
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公开(公告)号: EP2946014A2公开(公告)日: 2015-11-25
- 发明人: HOGE, Stephen G. , CHAKRABORTY, Tirtha , FREDERICK, Joshua P. , JOHN, Matthias , DE FOUGEROLLES, Antonin
- 申请人: Moderna Therapeutics, Inc.
- 申请人地址: 320 Bent Street Cambridge, Massachusetts 02141 US
- 专利权人: Moderna Therapeutics, Inc.
- 当前专利权人: Moderna Therapeutics, Inc.
- 当前专利权人地址: 320 Bent Street Cambridge, Massachusetts 02141 US
- 代理机构: Hoffmann Eitle
- 优先权: US201361753661P 20130117; US201361754159P 20130118; US201361781097P 20130314; US201361829334P 20130531; US201361839893P 20130627; US201361842733P 20130703; US201361857304P 20130723
- 国际公布: WO2014113089 20140724
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C12N15/85 ; C07K14/47 ; C07K14/82 ; A61K31/711 ; A61K31/7105 ; A61K31/7115 ; A61K38/16 ; A61K48/00
摘要:
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of signal-sensor polynucleotides, primary transcripts and mmRNA molecules.
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