- 专利标题： NAPHTHYL-AZO MODIFICATIONS FOR ANTISENSE COMPOUNDS
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申请号： EP14708460.2申请日： 2014-02-24
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公开(公告)号： EP2959000B1公开(公告)日： 2018-08-15
- 发明人: BEHLKE, Mark, Aaron , LENNOX, Kimberly, Ann , JACOBI, Ashley, Mae , OWCZARZY, Richard , WALDER, Joseph, Alan
- 申请人： Integrated DNA Technologies Inc. , Behlke, Mark Aaron , Lennox, Kimberly Ann , Jacobi, Ashley Mae , Owczarzy, Richard , Walder, Joseph Alan
- 申请人地址： 1710 Commercial Park Coralville, IA 52241 US
- 专利权人： Integrated DNA Technologies Inc.,Behlke, Mark Aaron,Lennox, Kimberly Ann,Jacobi, Ashley Mae,Owczarzy, Richard,Walder, Joseph Alan
- 当前专利权人： Integrated DNA Technologies Inc.,Behlke, Mark Aaron,Lennox, Kimberly Ann,Jacobi, Ashley Mae,Owczarzy, Richard,Walder, Joseph Alan
- 当前专利权人地址： 1710 Commercial Park Coralville, IA 52241 US
- 代理机构： Zwicker, Jörk
- 优先权： US201313776397 20130225
- 国际公布： WO2014130945 20140828
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/00
摘要：
The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
公开/授权文献
- EP2959000A1 MODIFICATIONS FOR ANTISENSE COMPOUNDS 公开/授权日：2015-12-30
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