发明公开
- 专利标题： Quantification of misfolded TNFR2:Fc
- 专利标题（中）： Quantifizierung von fehlgefaltetem TNFR2：Fc
-
申请号： EP14177696.3申请日： 2014-07-18
-
公开(公告)号： EP2975050A1公开(公告)日： 2016-01-20
- 发明人: Rupprechter, Alfred , Fuchs, Michael , Lamanna, William , Holzmann, Johann , Posch, Christoph , Toll, Hansjörg , Mayer, Robert
- 申请人： SANDOZ AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： SANDOZ AG
- 当前专利权人： SANDOZ AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Wichmann, Hendrik
- 主分类号： C07K14/715
- IPC分类号： C07K14/715 ; C07K1/16
摘要：
The present invention is directed to methods for determining the relative amount of wrongly disulphide bridged TNFR2:Fc in a sample of TNFR2:Fc, a fusion protein which is used in a variety of therapeutic applications. In addition, the invention pertains to a method for purifying TNFR2:Fc using said method for determining the percentage of wrongly disulphide bridged TNFR2:Fc, and to TNFR2:Fc compositions obtained thereby.
公开/授权文献
- EP2975050B1 Quantification of misfolded TNFR2:Fc 公开/授权日：2019-05-29
信息查询
