发明公开
- 专利标题： SUBSTITUTED BIARYL COMPOUND
- 专利标题（中）： SUBSTITUIERTE BIARYLVERBINDUNG
-
申请号： EP14775434.5申请日： 2014-03-28
-
公开(公告)号： EP2980075A1公开(公告)日： 2016-02-03
- 发明人: SHIBAKAWA, Nobuhiko , YONEDA, Kenji , KATSUBE, Tetsushi , KANDA, Tomoko , ITO, Koji , YAMAMOTO, Kiyoshi , IWASE, Noriaki , USHIYAMA, Shigeru
- 申请人： UBE Industries, Ltd.
- 申请人地址： 1978-96 Oaza Kogushi Ube-shi Yamaguchi 755-8633 JP
- 专利权人： UBE Industries, Ltd.
- 当前专利权人： UBE Industries, Ltd.
- 当前专利权人地址： 1978-96 Oaza Kogushi Ube-shi Yamaguchi 755-8633 JP
- 代理机构： Hoffmann Eitle
- 优先权： JP2013069363 20130328; JP2013228489 20131101
- 国际公布： WO2014157672 20141002
- 主分类号： C07D213/74
- IPC分类号： C07D213/74 ; A61K31/4436 ; A61K31/444 ; A61P11/00 ; A61P43/00 ; C07D409/12
摘要：
The present invention provides a substituted biaryl compound of general formula (I):
wherein, R 1 , W, R 2 , and Z are as defined in the claims and the description, or a pharmacologically acceptable salt thereof. The compound according to the present invention has an excellent inhibition effect of pulmonary fibroblast proliferation, and is therefore useful as a therapeutic agent and/or a prophylactic agent for interstitial pneumonia and pulmonary fibrosis.
wherein, R 1 , W, R 2 , and Z are as defined in the claims and the description, or a pharmacologically acceptable salt thereof. The compound according to the present invention has an excellent inhibition effect of pulmonary fibroblast proliferation, and is therefore useful as a therapeutic agent and/or a prophylactic agent for interstitial pneumonia and pulmonary fibrosis.
信息查询
IPC分类:
