发明公开
EP2983693A1 Sept4/ARTS AS A TUMOR SUPPRESSOR IN THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF HEPATIC DISORDERS
审中-公开
9月4日/ ARTS作为肿瘤抑制剂在肝脏疾病的诊断，预后和治疗中的应用
- 专利标题： Sept4/ARTS AS A TUMOR SUPPRESSOR IN THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF HEPATIC DISORDERS
- 专利标题（中）： 9月4日/ ARTS作为肿瘤抑制剂在肝脏疾病的诊断，预后和治疗中的应用
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申请号： EP14782569.9申请日： 2014-04-07
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公开(公告)号： EP2983693A1公开(公告)日： 2016-02-17
- 发明人: LARISCH, Sarit , STELLER, Hermann
- 申请人： Carmel-Haifa University Economic Corporation Ltd. , The Rockefeller University
- 申请人地址： Eshkol Building Haifa University 31905 Haifa IL
- 专利权人： Carmel-Haifa University Economic Corporation Ltd.,The Rockefeller University
- 当前专利权人： Carmel-Haifa University Economic Corporation Ltd.,The Rockefeller University
- 当前专利权人地址： Eshkol Building Haifa University 31905 Haifa IL
- 代理机构： Bentham, Andrew
- 优先权： US201361809587P 20130408
- 国际公布： WO2014167564 20141016
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P1/16 ; A61P35/00 ; C12Q1/68 ; G01N33/574
摘要：
The invention relates to methods for the diagnosis and prognosis of hepatic disorder and associated pathologies as well as of a solid proliferative disorder in a mammalian subject. More specifically, the methods of the invention are based on determining the expression, methylation of ARTS as well as histone trimethylation. The invention further provides therapeutic methods for treating said disorders.
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