发明公开
- 专利标题: PREDICTING IMMUNOGENICITY OF T CELL EPITOPES
- 专利标题(中): 预测T细胞表位的免疫原性
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申请号: EP14722117.0申请日: 2014-05-07
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公开(公告)号: EP2994159A1公开(公告)日: 2016-03-16
- 发明人: SAHIN, Ugur , TADMOR, Arbel David , CASTLE, John Christopher , BOEGEL, Sebastian , LÖWER, Martin
- 申请人: BioNTech AG , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址: An der Goldgrube 12 55131 Mainz DE
- 专利权人: BioNTech AG,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人: BioNTech AG,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人地址: An der Goldgrube 12 55131 Mainz DE
- 代理机构: Schnappauf, Georg
- 优先权: PCT/EP2013/001400 20130510
- 国际公布: WO2014180569 20141113
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; G06F19/18
摘要:
The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and. thus, in the context of personalized cancer vaccines.
公开/授权文献
- EP2994159B1 PREDICTING IMMUNOGENICITY OF T CELL EPITOPES 公开/授权日:2021-03-10
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