发明公开
EP3008168A4 SC- CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
审中-公开
SC-ZELLEN SOWIE ZUSAMMENSETZUNGEN UND VERFAHREN ZUR ERZEUGUNG DAVON
- 专利标题： SC- CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME
- 专利标题（中）： SC-ZELLEN SOWIE ZUSAMMENSETZUNGEN UND VERFAHREN ZUR ERZEUGUNG DAVON
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申请号： EP14819763申请日： 2014-06-11
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公开(公告)号： EP3008168A4公开(公告)日： 2017-05-31
- 发明人: PETERSON QUINN P , PAGLIUCA FELICIA J , MELTON DOUGLAS A , MILLMAN JEFFREY R , SEGEL MICHAEL SARIS , GÜRTLER MADS , REZANIA ALIREZA , FRYER BENJAMIN
- 申请人： HARVARD COLLEGE , JANSSEN BIOTECH INC
- 专利权人： HARVARD COLLEGE,JANSSEN BIOTECH INC
- 当前专利权人： HARVARD COLLEGE,JANSSEN BIOTECH INC
- 优先权： US201361833898 2013-06-11; US201461972212 2014-03-28
- 主分类号： C12N5/02
- IPC分类号： C12N5/02 ; C12N5/00 ; C12N5/071 ; C12N5/0735 ; C12N5/074
摘要：
Disclosed herein is a method for differentiating PDX1-positive pancreatic progenitor cells into NKX6.1 positive pancreatic progenitor cells with a culture medium comprising a) KGF and b) SANT1, wherein the culture medium is substantially free of (1) a Protein Kinase C (PKC) Activator or (2) a BMP signaling pathway inhibitor.
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