发明公开
- 专利标题： ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES
- 专利标题（中）： 抗真菌药物 - 抗生素抗生素
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申请号： EP15162049.9申请日： 2006-11-17
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公开(公告)号： EP3023497A1公开(公告)日： 2016-05-25
- 发明人: LAZARIDES, Elias , WOODS, Catherine , BERNARD, Mark
- 申请人： Glenmark Pharmaceuticals S.A.
- 申请人地址： Chemin de la Combeta, 5 2300 La Chaux-de-Fonds CH
- 专利权人： Glenmark Pharmaceuticals S.A.
- 当前专利权人： Glenmark Pharmaceuticals S.A.
- 当前专利权人地址： Chemin de la Combeta, 5 2300 La Chaux-de-Fonds CH
- 代理机构： Latscha Schöllhorn Partner AG
- 优先权： US738303P 20051118
- 主分类号： C12N15/13
- IPC分类号： C12N15/13 ; A61K39/395 ; A61P19/00 ; A61P35/00 ; A61P37/02 ; C07K14/705 ; C07K14/78 ; C07K16/28 ; C12N15/63 ; C12N5/10 ; C12P21/08
摘要：
The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.
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