发明公开
- 专利标题： SALTS OF DASATINIB IN CRYSTALLINE FORM
- 专利标题（中）： SALZE AUS DASATINIB IN KRISTALLINER FORM
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申请号： EP14741630.9申请日： 2014-07-22
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公开(公告)号： EP3024830A2公开(公告)日： 2016-06-01
- 发明人: HAFNER, Andreas , BLATTER, Fritz , SZELAGIEWICZ, Martin , SIEBENHAAR, Bernd , CHIODO, Tiziana , HINTERMANN, Tobias , SALVADOR, Beate , VOSSEN, Marcus
- 申请人： BASF SE
- 申请人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 代理机构： Upschulte, Manfred Alois
- 优先权： EP13178021 20130725
- 国际公布： WO2015011120 20150129
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; A61K31/506
摘要：
The present invention primarily relates to molecular crystalline substances, preferably salts of Dasatinib in crystalline form, comprising a compound of formula 1, preferably a cation of a compound of formula 1, and a second compound selected from the group consisting of glutaric acid, nicotinic acid and saccharin, preferably an anion thereof. The Invention is further related to pharmaceutical compositions comprising such a substance. Furthermore, the Invention relates to processes for preparing said substances. The invention also relates to several aspects of using said substances or pharmaceutical compositions to treat a disease.
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