- 专利标题： A RAPID QUANTITATIVE ASSAY TO MEASURE CFTR FUNCTION IN A PRIMARY INTESTINAL CULTURE MODEL
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申请号： EP15194157.2申请日： 2012-12-19
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公开(公告)号： EP3045912B1公开(公告)日： 2018-09-19
- 发明人: BEEKMAN, Jeffrey Matthijn , DEKKERS, Johanna Florentia , VAN DER ENT, Cornelis Korstiaan , CLEVERS, Johannes Carolus
- 申请人： UMC Utrecht Holding B.V. , Koninklijke Nederlandse Akademie van Wetenschappen
- 申请人地址： Yalelaan 40 3584 CM Utrecht NL
- 专利权人： UMC Utrecht Holding B.V.,Koninklijke Nederlandse Akademie van Wetenschappen
- 当前专利权人： UMC Utrecht Holding B.V.,Koninklijke Nederlandse Akademie van Wetenschappen
- 当前专利权人地址： Yalelaan 40 3584 CM Utrecht NL
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US201161577110P 20111219; US201161579661P 20111223
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; C12N5/00
摘要：
The invention relates to an assay for diagnosing a disease or affliction that affects fluid uptake or secretion or for studying the effectiveness of one or more drugs for treating the disease or affliction, wherein the assay comprises measuring swelling of one or more organoids.
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