发明授权
- 专利标题： PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS
- 专利标题（中）： 作为JAK1抑制剂的哌啶-4-基亚甲基噻吩衍生物
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申请号： EP15195698.4申请日： 2011-03-09
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公开(公告)号： EP3050882B1公开(公告)日： 2018-01-31
- 发明人: HUANG, Taisheng , XUE, Chu-Biao , WANG, Anlai , KONG, Ling , YE, Hai Fen , YAO, Wenqing , RODGERS, James D. , SHEPARD, Stacey , WANG, Haisheng , SHAO, Lixin , LI, Hui-Yin , LI, Qun
- 申请人： Incyte Holdings Corporation
- 申请人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 专利权人： Incyte Holdings Corporation
- 当前专利权人： Incyte Holdings Corporation
- 当前专利权人地址： 1801 Augustine Cut-Off Wilmington, DE 19803 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US312588P 20100310; US415602P 20101119
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; A61K31/437 ; A61K31/519 ; A61P3/10 ; A61P17/00 ; A61P19/02 ; A61P29/00 ; A61P35/00
摘要：
The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
公开/授权文献
- EP3050882A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS 公开/授权日：2016-08-03
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