发明公开
EP3052500A1 INHIBITEURS DE 5'-NUCLÉOTIDASES ET LEURS UTILISATIONS THÉRAPEUTIQUES
有权
5-NUKLEOTIDASE-HEMMER UNDEREREUTISCHE VERWENDUNGEN DAVON
- 专利标题： INHIBITEURS DE 5'-NUCLÉOTIDASES ET LEURS UTILISATIONS THÉRAPEUTIQUES
- 专利标题（英）： 5'-nucleotidase inhibitors and therapeutic uses thereof
- 专利标题（中）： 5-NUKLEOTIDASE-HEMMER UNDEREREUTISCHE VERWENDUNGEN DAVON
-
申请号： EP14796208.8申请日： 2014-09-29
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公开(公告)号： EP3052500A1公开(公告)日： 2016-08-10
- 发明人: CHALOIN, Laurent , PEYROTTES, Suzanne , LIONNE, Corinne , MARTON, Zsuzsanna , EGRON, David , GUILLON, Rémi , PERIGAUD, Christian , DUMONTET, Charles , JORDHEIM, Lars Petter , KRIMM, Isabelle
- 申请人： Centre National de la Recherche Scientifique , Les Hospices Civils de Lyon , Ecole Normale Supérieure de Lyon , Université Claude Bernard Lyon 1 , Université de Montpellier 1
- 申请人地址： 3, rue Michel-Ange 75794 Paris Cedex 16 FR
- 专利权人： Centre National de la Recherche Scientifique,Les Hospices Civils de Lyon,Ecole Normale Supérieure de Lyon,Université Claude Bernard Lyon 1,Université de Montpellier 1
- 当前专利权人： Centre National de la Recherche Scientifique,Les Hospices Civils de Lyon,Ecole Normale Supérieure de Lyon,Université Claude Bernard Lyon 1,Université de Montpellier 1
- 当前专利权人地址： 3, rue Michel-Ange 75794 Paris Cedex 16 FR
- 代理机构： Cabinet Plasseraud
- 优先权： FR1359472 20131001
- 国际公布： WO2015049447 20150409
- 主分类号： C07D473/34
- IPC分类号： C07D473/34 ; A61K31/52
摘要：
The subject matter of the present invention is compounds which have a 6-aminopurine backbone corresponding to formula (I): in which R
1 , R
2 , R
3 , X, Y and Z are as defined in any one of Claims 1 to 5, and Ar is a biphenyl or a naphthyl which may be substituted with R
3 , for use in the treatment of cancer.
1 , R
2 , R
3 , X, Y and Z are as defined in any one of Claims 1 to 5, and Ar is a biphenyl or a naphthyl which may be substituted with R
3 , for use in the treatment of cancer.
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