发明公开
EP3059593A1 MASS SPECTROMETRY OF BRAIN NATRIURETIC PEPTIDE IN BLOOD USING CHEMICAL ISOTOPIC SUBSTITUTION
审中-公开
MASSENSPEKTROMETRIE VON GEHIRN-NATRIURETISCHEM PIPTID IM BLUT DURCH CHEMISCHE ISOTOPISCHE SUBSTITUTION
- 专利标题： MASS SPECTROMETRY OF BRAIN NATRIURETIC PEPTIDE IN BLOOD USING CHEMICAL ISOTOPIC SUBSTITUTION
- 专利标题（中）： MASSENSPEKTROMETRIE VON GEHIRN-NATRIURETISCHEM PIPTID IM BLUT DURCH CHEMISCHE ISOTOPISCHE SUBSTITUTION
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申请号： EP14854826.6申请日： 2014-09-18
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公开(公告)号： EP3059593A1公开(公告)日： 2016-08-24
- 发明人: KANG, Dukjin , KIM, Sook-Kyung , LEE, Sun Young
- 申请人： Korea Research Institute of Standards and Science
- 申请人地址： Gajeong-dong 267 Gajeong-ro Yuseong-gu Daejeon 305-340 KR
- 专利权人： Korea Research Institute of Standards and Science
- 当前专利权人： Korea Research Institute of Standards and Science
- 当前专利权人地址： Gajeong-dong 267 Gajeong-ro Yuseong-gu Daejeon 305-340 KR
- 代理机构： dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
- 优先权： KR20130123364 20131016
- 国际公布： WO2015056889 20150423
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; G01N33/53 ; G01N27/62 ; G01N30/72
摘要：
The present invention relates to a quantitative analysis method on the basis of an isotope-dilution mass spectrometry using a chemical isotope labelling method for a brain natriuretic peptide which is widely used as a biomarker for diagnosis and prognostic evaluation of cardiovascular-associated diseases. The quantitative analysis method of a brain natriuretic peptide in blood using a chemical isotope labelling technique is a brain natriuretic peptide-specific quantitative analysis technique which is more accurate than a conventional immunoassay using an antibody.
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