发明公开
- 专利标题： PERSONALIZED IMMUNOTHERAPY AGAINST SEVERAL NEURONAL AND BRAIN TUMORS
- 专利标题（中）： 上个世纪以来的人造血统
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申请号： EP14792834.5申请日： 2014-11-03
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公开(公告)号： EP3066115A2公开(公告)日： 2016-09-14
- 发明人: WEINSCHENK, Toni , FRITSCHE, Jens , WALTER, Steffen , HILF, Norbert , SCHORR, Oliver , SINGH, Harpreet , KUTTRUFF-COQUI, Sabrina , SONG, Colette
- 申请人： Immatics Biotechnologies GmbH
- 申请人地址： Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 专利权人： Immatics Biotechnologies GmbH
- 当前专利权人： Immatics Biotechnologies GmbH
- 当前专利权人地址： Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 代理机构： Krauss, Jan
- 优先权： GB201319446 20131104; US201361899680P 20131104
- 国际公布： WO2015063302 20150507
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; A61K38/17 ; A61K39/00 ; C07K7/06 ; C07K7/08
摘要：
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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