发明公开
- 专利标题: NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS
- 专利标题(中): 使用吲哚氧基苯甲酰氯
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申请号: EP14802432.6申请日: 2014-11-24
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公开(公告)号: EP3074375A1公开(公告)日: 2016-10-05
- 发明人: LINGARD, Iain , HAMPRECHT, Dieter
- 申请人: Boehringer Ingelheim International GmbH
- 申请人地址: Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构: Simon, Elke Anna Maria
- 优先权: EP13194945 20131128
- 国际公布: WO2015078802 20150604
- 主分类号: C07C255/54
- IPC分类号: C07C255/54 ; C07C317/18 ; C07C317/22 ; C07C317/44 ; C07C235/46 ; C07C235/48 ; C07C62/34 ; C07D309/12 ; C07D309/14 ; C07D215/20 ; C07D231/12 ; C07D231/56 ; C07D249/08 ; C07D257/04 ; C07D271/06
摘要:
A compound of formula I, wherein the groups R1, R2, R3, X, m, and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
公开/授权文献
- EP3074375B1 NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS 公开/授权日:2018-04-04
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