发明公开
- 专利标题: SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF
- 专利标题(中): 取代苯甲酰胺及其方法使用
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申请号: EP14865855申请日: 2014-11-26
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公开(公告)号: EP3074377A4公开(公告)日: 2017-04-19
- 发明人: ANDREZ JEAN-CHRISTOPHE , BICHLER PAUL ROBERT , CHEN CHIEN-AN , CHOWDHURY SULTAN , DECKER SHANNON MARIE , DEHNHARDT CHRISTOPH MARTIN , FOCKEN THILO , GRIMWOOD MICHAEL EDWARD , HEMEON IVAN WILLIAM , JIA QI , LI JUN , LIU ZHIGUO , ORTWINE DANIEL F , SAFINA BRIAN , SUTHERLIN DANIEL , SHENG TAO , SUN SHAOYI , WHITE ANDREW D , WILSON MICHAEL SCOTT , ZENOVA ALLA YUREVNA , ZHU JIUXIANG
- 申请人: GENENTECH INC , XENON PHARMACEUTICALS INC
- 专利权人: GENENTECH INC,XENON PHARMACEUTICALS INC
- 当前专利权人: GENENTECH INC,XENON PHARMACEUTICALS INC
- 优先权: CN2013001452 2013-11-27; CN2013088062 2013-11-28; CN2014090171 2014-11-03
- 主分类号: C07D205/04
- IPC分类号: C07D205/04 ; A61K31/337 ; A61K31/397 ; A61K31/4015 ; A61K31/415 ; A61K31/4412 ; A61K31/495 ; A61P25/04 ; C07D207/12 ; C07D211/42 ; C07D233/68 ; C07D237/08 ; C07D241/04 ; C07D305/08
摘要:
The invention provides compounds having the general formula I: and pharmaceutically acceptable salts thereof, wherein the variables RA, RAA, subscript n, ring A, X2, L, subscript m, X1, R1, R2, R3, R4, R5, and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compactions.
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