发明公开
- 专利标题： IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
- 专利标题（中）： 咪唑并吡啶衍生物作为TNF活性调节剂
-
申请号： EP14825109.3申请日： 2014-12-08
-
公开(公告)号： EP3080123A1公开(公告)日： 2016-10-19
- 发明人: DELIGNY, Michaël Louis Robert , HEER, Jag Paul , JACKSON, Victoria Elizabeth , KROEPLIEN, Boris , LECOMTE, Fabien Claude , PORTER, John Robert
- 申请人： UCB Biopharma SPRL
- 申请人地址： Allée de la Recherche 60 1070 Brussels BE
- 专利权人： UCB Biopharma SPRL
- 当前专利权人： UCB Biopharma SPRL
- 当前专利权人地址： Allée de la Recherche 60 1070 Brussels BE
- 代理机构： Duckworth, Timothy John
- 优先权： GB201321741 20131209
- 国际公布： WO2015086509 20150618
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P29/00
摘要：
A series of substituted 3H imidazo[4,5-b]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
信息查询
