发明公开
EP3080290A1 OVER-EXPRESSION OF A FATTY ACID TRANSPORTER GENE AND OF GENES ENCODING ENZYMES OF THE BETA-OXIDATION PATHWAY FOR HIGHER PRODUCTION OF RIBOFLAVIN VIA FERMENTATION OF EREMOTHECIUM
审中-公开
和脂肪酸转运蛋白基因编码基因β-氧化的信号路径的增加酶的生产发酵BY假囊核黄素的方式表达
- 专利标题： OVER-EXPRESSION OF A FATTY ACID TRANSPORTER GENE AND OF GENES ENCODING ENZYMES OF THE BETA-OXIDATION PATHWAY FOR HIGHER PRODUCTION OF RIBOFLAVIN VIA FERMENTATION OF EREMOTHECIUM
- 专利标题（中）： 和脂肪酸转运蛋白基因编码基因β-氧化的信号路径的增加酶的生产发酵BY假囊核黄素的方式表达
-
申请号： EP14835475.6申请日： 2014-12-04
-
公开(公告)号： EP3080290A1公开(公告)日： 2016-10-19
- 发明人: HOFF, Birgit , MOLT, Andrea , HAEFNER, Stefan , ZELDER, Oskar
- 申请人： BASF SE
- 申请人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： Carl-Bosch-Strasse 38 67056 Ludwigshafen am Rhein DE
- 代理机构： Maiwald Patentanwalts GmbH
- 优先权： EP13196262 20131209
- 国际公布： WO2015086427 20150618
- 主分类号： C12P25/00
- IPC分类号： C12P25/00
摘要：
The present invention relates to a method of producing riboflavin in a genetically modified organism of the genus Eremothecium, wherein said genetic modification is linked to the fatty acid uptake and/or beta-oxidation pathway of said organism, comprising growing said organisms in a culture medium and isolating riboflavin from the culture medium. The invention further relates to a method of providing a riboflavin accumulating organism belonging to the genus Eremothecium by genetically modifying said organism, to organisms obtained by such a method, as well as the use of such genetically modified organisms for increasing the accumulation of riboflavin.
信息查询
