发明公开
- 专利标题： SPIRO-OXAZOLONES
- 专利标题（中）： 螺恶唑酮
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申请号： EP14815318.2申请日： 2014-12-16
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公开(公告)号： EP3083633A1公开(公告)日： 2016-10-26
- 发明人: RUNTZ-SCHMITT, Valerie , SCHNIDER, Patrick , DOLENTE, Cosimo , FASCHING, Bernhard
- 申请人： F.Hoffmann-La Roche AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F.Hoffmann-La Roche AG
- 当前专利权人： F.Hoffmann-La Roche AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Müller-Afraz, Simona
- 优先权： EP13198604 20131219
- 国际公布： WO2015091411 20150625
- 主分类号： C07D491/10
- IPC分类号： C07D491/10 ; C07D491/12 ; C07D498/10 ; A61K31/438 ; A61P25/00
摘要：
The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.
公开/授权文献
- EP3083633B1 SPIRO-OXAZOLONES 公开/授权日：2017-11-29
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