发明公开
EP3105350A2 TRANSCRIPTOMIC BIOMARKERS, METHOD FOR DETERMINATION THEREOF AND USE OF TRNASCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT OF DEVELOPING POST-INFRACTION HEART FAILURE
审中-公开
转录生物标记物的方法来确定哪些和心衰的发展评估个体风险转录组生物标记物的使用后梗死
- 专利标题： TRANSCRIPTOMIC BIOMARKERS, METHOD FOR DETERMINATION THEREOF AND USE OF TRNASCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT OF DEVELOPING POST-INFRACTION HEART FAILURE
- 专利标题（中）： 转录生物标记物的方法来确定哪些和心衰的发展评估个体风险转录组生物标记物的使用后梗死
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申请号： EP15712187.2申请日： 2015-02-12
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公开(公告)号： EP3105350A2公开(公告)日： 2016-12-21
- 发明人: BURZYNSKA, Beata , GÓRA, Monika , MACIEJAK, Agata , TULACZ, Dorota , KILISZEK, Marek , MICHALAK, Marcin , OPOLSKI, Grzegorz , MATLAK, Krzysztof , DOBRZYCKI, Slawomir
- 申请人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Warszawski Uniwersytet Medyczny , Uniwersytet Medyczny W Bia Ymstoku
- 申请人地址： Adolfa Pawinskiego 5A 02-106 Warszawa PL
- 专利权人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk,Warszawski Uniwersytet Medyczny,Uniwersytet Medyczny W Bia Ymstoku
- 当前专利权人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk,Warszawski Uniwersytet Medyczny,Uniwersytet Medyczny W Bia Ymstoku
- 当前专利权人地址： Adolfa Pawinskiego 5A 02-106 Warszawa PL
- 代理机构： Kaminski, Zbigniew
- 优先权： PL40716314 20140212
- 国际公布： WO2015121737 20150820
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The invention relates to biomarkers for individual risk assessment of the development of post-infarction heart failure, the method of determining the markers in samples of biological material collected from a patient. Further, the invention relates to a use of the biomarkers in the diagnosis (expression level of the gene) that correlate with the developing post-infarction heart failure, and enable prevention of heart disease based on a genetic marker and a method for predicting the risk of developing a heart failure for post-infarction patients. Also a method for optimizing the treatment of cardiac patients with the use of the means of the invention is disclosed.
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